| 2010 |
12
| - Development of oral moisturizers
- Research and development of high-sensitivity and system integration technologies for MEMS sensor devices.
- The effects of physical stimulation therapy on oral soft and hard tissues.
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|---|
| 2011 |
10
| - Development of a pre-operative verification system aimed at optimizing implant design
- Physiological and clinical studies on salivary secretion using experimental animals and humans
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|---|
| 2012 |
10
| - Development of a water-flow ultrasonic plaque remover that enables the treatment of peri-implantitis.
- Research on the relationship between the quality of human-derived samples and dental clinical indicators
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|---|
| 2013 |
10
|
- Research on verifying malnutrition markers using salivary protein levels in the elderly.
- Development of novel bioglass-based cements for dental applications
- Evaluation of chewing ability in denture wearers
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|---|
| 2014 |
9
|
- Verification of the effectiveness of salt toothpaste using soap as a foaming agent.
- Research on creating highly specific and sensitive antibodies against IL-1, IL-6, and TNF-α.
- Health management systems and services that utilize "tongue diagnosis"
- Clinical applications of oral mucosal observation devices using optical means and development of diagnostic methods, etc.
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|---|
| 2015 |
9
|
- The effect of relaxation systems on stress reduction during dental examinations.
- Evaluation of systems for oral cancer detection
- Research on community-based comprehensive care for eating, swallowing, and nutrition in the elderly.
- Evaluation of the usefulness of chewing and swallowing training foods in patients after head and neck tumor surgery, etc.
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|---|
| 2016 |
4
|
- Clinical applications of oral mucosal observation devices using optical means and development of diagnostic methods.
- Examining the improvement of QOL (quality of life) for the elderly through oral function management.
- Development of a recurrent education program for dental hygienists on oral function management in collaboration with medical and dental professionals.
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|---|
| 2017 |
7
|
- Evaluation of the usefulness of novel bioglass-based cement and preliminary clinical research study
- Research on the development of a gentle toothpaste using β-glucan to suppress the worsening of periodontal disease.
- Research on the search for effective ingredients and bases for suppressing pain in stomatitis
- Ultra-compact endoscopic imaging using advanced image restoration technology
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|---|
| 2018 |
11
|
- Current Status and Dissemination of Pathological Examination in Regional Dental Care
- Development of safe preventive agents and methods for periodontal disease
- Elucidating the pathogenesis of oral diseases through molecular biological analysis
- Reconstruction of periodontal tissue using allogeneic periodontal ligament-derived mesenchymal stem cell sheets.
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|---|
| 2019 |
12
|
- A study on chewing and swallowing exercise therapy for residents of nursing care facilities for the elderly.
- Development of an AI-powered cloud-based oral mucosal disease diagnostic support system for general practitioners.
- Identification of the effects of bee-related materials such as royal jelly on mouse denervated skeletal muscle atrophy and cardiotoxin-induced skeletal muscle regeneration models.
- Research and development of oral health management utilizing the functions of micro- and nanobubbles
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|---|
| 2020 |
9
|
- Research on the effects of royal jelly on stemness and stem cell niche of skeletal muscle stem cells
- Detailed analysis of the molecular mechanisms of MMP expression suppression in chondrocytes and osteoclast differentiation modification via stromal cells by Altz.
- Research on the clinical application of the oral moisture meter Mucus
- Verification of the effectiveness of a new periodontal disease examination method in dental checkups for working adults (periodontal disease screening).
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|---|
| 2021 |
9
|
- Current status and dissemination of pathological examinations to contribute to the early detection of oral cancer in community dental care.
- Development of toothpaste and mouthwash using β-glucan that are effective in preventing and treating the worsening of periodontal disease.
- Development of safe preventive agents and methods for periodontal disease
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|---|
| 2022 |
7
|
- Basic research on traditional Chinese medicine that regulates age-related changes in salivary secretion function
- Association between coffee consumption habits and long-term prognosis in diabetic patients using a large-scale genomic cohort study.
- Treatment outcomes in root canal treatment under sterile conditions: A multicenter prospective cohort study
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|---|
| 2023 |
6
|
- Research on elucidating the function of sebacic acid in determining the fate of bone marrow-derived mesenchymal stem cells.
- The effect of leucine-containing nutritional supplements on improving oral function training in the elderly.
- Elucidation of the regulatory mechanism of MKP-5 involved in the suppression of MMP-13 expression in chondrocytes in Alzheimer's disease.
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|---|
| 2024 |
2
|
- Elucidation of the role of royal jelly in DNA methylation in C2C12 cell plasticity.
- Development of toothpaste and mouthwash using β-glucan that are effective in preventing and reducing the progression of periodontal disease.
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