Undergraduate and Graduate Schools Curriculum

The education curriculum of the Graduate School of Dentistry aims to foster the ability of people to independently take a leading role in research in their fields of specialty while conducting research in academic theory and applications in the field of dentistry, to delve into this field, and contribute widely to human services and the advancement of culture.

Primary Research Topics

Doctoral Course(Dental Medicine)Course Term: 4 years

Research Field Primary Research Topics
Comprehensive Dental Research
  • ・Research in the performance of medical treatment
    Research in patient behavior and the diagnosis/treatment system
    ・Research concerning communication in medical treatment
    ・Professionalism studies
    ・Human subject and physical simulation studies
    ・Dental/medical education research
    ・Comprehensive research in diagnosis and treatment
Clinical Education Development and Research

・Study on education system of clinical clerkship
・Study on assessment system of clinical ability for students in clinical dental education
・Study on education system to acquire clinical skills for performance of primary care in dentistry
・Study on medical risk management in clinical clerkship
・Study on drug discovery for prevention and treatment of periodontal diseases
・Study on relationships between oral and systemic health
・Psychological study of patients
・Psychological study of dental students

Periodontology ・Mechanism of periodonntal tissue destruction in periodontitis
・Effects of periodontal disease on systemic health 
・Development of devices for periodontal diagnosis
・Development of periodontal tissue regeneration therapy
Endodontics and Restorative Dentistry

・Development of acquisition methods of diagnostic and therapeutic techniques necessary for conservative dentistry medical specialists
・Development of new treatment techniques and biomaterials
・Development of dental pulp and periapical tissue regeneration therapy
・Analysis of dental pulp and periapical tissue disease biology

Dysphagia Rehabilitation

・Research on rehabilitation for dysphagia
・Research on the effects of systemic and oral intervention for postoperative head and neck tumors
・Research on rehabilitation for pill dysphagia
・Research on the effects of intervention for oral hypofunction
・Research on the effects of oral intervention in elderly persons long-term care
・Research on the effects of oral interventions in end-of-life care
・Research on new oral hygiene management techniques
・Research on the relationship between nutrition and oral function
・Research on oriental medicine approaches to oral diseases

Occlusions and Maxillofacial Reconstruction

・Investigation of jaw position in relation to obstractive sleep apnea syndrome
・Clinical evaluation of dental magnetic attachment
・Splint therapy for temporomandibular disorders and effects on brain function
・Effects of habitual mastication on mandibular movement
・Clinical research concerning retention and stabilization of complete dentures

Oral Reconstructive Prosthodontics

・Research on treatment with immediate oral implants
・Research on xerostomia and physiological functioning of salivary glands
・Research on implant treatment risk assessment
・Research on diagnosis and treatment of parafunction
・Oral health-related quality of life assessment

Biomaterials

・Development of novel CAD/CAM materials
・Development of novel implant materials
・Characterization for bonding of dental materials
・Development of  artificial enamel and dentin
・Imparting antimicrobial properties to dendal materials and instruments
・Applications of electrolyzed water in dentistry
・Development of novel ponding pretreatment device for dental adhesion

Community Oral Health Development ・Epidemiological study of the relationship between oral and systemic health/sarcopenia of the elderly in the region
・Study of predictive model development for oral frailty using spatial information analysis
・Epidemiological study on the association between chronobiology and oral/systemic health condition
・Study of sociopsychology factor analysis relating to ozostomia
・Clinical research on usefulness of a novel device for odor detection on assessment of periodontal diseases
Clinical Epidemiology ・Clinical epidemiological study and dental practice-based research
・International comparative research on evaluation of diagnosis, treatment effectiveness, and prognosis
・Research on evidence-practice gap
Comprehensive Internal Medicine ・Epidemiological study concerning oral and systemic health condition of the elderly.
Anatomy

・Molecular structure of tooth generation
・Elucidation of emergence mechanisms of cleft lip and cleft palate
・Signal transduction in mammalian taste buds
・Molecular biology of taste bud development and taste receptor structures
・Role of ATP and contribution of ATP receptor expression in oral sensation (taste, pain, etc.)
・Cellular biological and ultra-structural studies of hard tissue and oral mucosa

Physiology

・Mechanism of salivary secretion
・Cognitive mechanism of food texture perception
・Neurological mechanism of orofacical pain
・Pathophysiology of oral mucositis and development of pain relief drugs
・Function of mastication and swallowing

Biochemistry

・Bone and skeletal muscle metabolism
・Fate decision mechanisms of mesenchymal stem cells
・The function of taste receptors in musculoskeletal tissues
・The function of mesenchymal tissue in organogenesis of teeth and hair follicle, etc.

Infections and Molecular Biology ・Regulatory mecanisms of sugar chain recognition on innate immune responses and bone and cartilage metabolism
・Regulatory mecanisms of bacrerial biofilm formation and drug resistance
・Oral bacterium and host cell interactions
・Development of novel strategy of diagnoses, treatment, and prevention for oral infectious diseases
・Application of three-dimensional culture systems for tissue regeneration and pathological model
Applied Pharmacology ・Drug development targeting intracellular transport in membrane molecules
・Regulatory mechanisms of metabolic and multi-organ networks
・Tumor suppressing effect and mechanism of action mediated by newly synthesized chemical compounds
Oral Pathology

・Clinical pathology research aimed at improving diagnostic precision of precancerous lesions
・Functional analysis of β-thymosins
・Molecular and histopathological analysis of oral diseases

Oral Functional Development

・Research on oral functional development and evaluation
・Research concerning lip-closing force, tongue pressure, and maxillofacial morphology in children
・Research on maxillofacial development
・Research on providing dental treatment to uncooperative children and children with disability
・Research on education in pediatric dentistry

Orofacial Functions and Orthodontics

・Research concerning pain arising from orthodontic treatment
・Study on remodeling of periodontal tissue during orthodontic tooth  movement
・Research concerning neuropeptides and bone remodeling
・Investigation of gene responsible for congenital anomaly associated with malocclusion and the function
・Clinical evaluation concerning with long-term stability of orthognathic treatment

Oral and Maxillofacial Radiology

・Research into MRI use for diagnosis of temporomandibular joint disorders
・Research into precise blood vessel disclosure using MR angiography
・Evaluation of clinical applications of MR sialography
・Molecular biological analysis of signaling of apoptotic cell death induced by ionizing radiation

Dental Anesthesiology and Pain Management ・Research on treatment method for nociplastic pain
・Elucidation of pain suppression mechanisms of ketamine for chronic pain
・Urltrasound nerve block in dentistry
・Research on the advantages of ketamine in general anesthesia
・The state of anesthesia education for dental hygienists
・Investigation of treatment method using botulinum toxin for odontopathy

Oral and Maxillofacial Surgery

・Research into development of novel cancer diagnosis system using electrochemical telomerase assay
・Research into development of a diagnostic support system for oral mucosal diseases
・Research into development of novel anti-cancer drug targeting telomere DNA
・Research into effects of indigenous oral bacteria on oral cancer
・Research into biological activity of magnesium hydroxide compound in osteogenesis
・Research into effects of natural surfactant on oral bacterium-derived biofilm

Oral Medicine

・Clinical research on jaw deformity (functional evaluation and sociopsychology evaluation)
・Development of computer-assisted oral surgical procedure
・Research on elucidating pathogenesis and establishing new treatment method for medication-related osteonecrosis of the jaw (MRONJ)
・Research on diagnosis of oral mucosal lesion using AI
・Fundamental research on oral cancer diagnosis and treatment

Health Promotion Sciences ・Activity of prefrontal cortex induced by visually guided direction-selective tongue-protrusion task
Oral Health Sciences

・Research on dental health policy
・immunological mechanisms of adipokines
・Research about the mechanism of atherosclerosis due to LPS and diabetes mellitus
・Eating habits of the patients receiving periodontal maintenance / SPT
・Relationship between oral function and general status in elderly person/medically compromised patient
・Investigation of the international education for dental hygienists
・Research on rehabilitations for dysphagia

Master’s Course(Oral Health Sciences)Course Term: 2 years

Primary Research Topics

● Research to clarify regional health issues concerning oral health care by understanding actual conditions of dental diseases and dental health care management at hospitals, facilities for the elderly, and at locations that provide regional dental health care, such as public health centers, municipal health centers, schools, and businesses

● Research on dental hygiene activities for lifelong oral health care management

● Research using cellular and molecular biology techniques and epidemiologic techniques to investigate immune response changes in abnormal energy metabolic states such as metabolic syndrome, especially the effects of various types of adipokines on immune cells

● Clinical and practical research regarding oral function improvement and eating and swallowing rehabilitations in accordance with various fields, life stages, and lifestyles*

● Basic research using molecular biology techniques, and clinical or epidemiological investigative study using epidemiologic techniques considered necessary to keep dental, oral, and overall body health, such as the development, maintenance, and recovery of eating functions, prevention of dental caries, prevention of lifestyle diseases causing dysphagia and conditions requiring care, and prevention of undernutrition potentially caused by oral complications

● Investigative research on thinking processes and multidisciplinary collaboration necessary for oral management during acute, convalescence, and maintenance phases*

● Research on patient-reported outcome (PRO) related to oral health

●Research on the effects of intervention in the oral function management with regards to end of life care*

●Investigation of oral hygiene and health management method to prevent aspiration pneumonia using salivary bacterial count*

  • *Those engaging in clinical research must possess necessary medical qualifications to practice medicine (as a dentist, dental hygienist, nurse, etc.).
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Contact

Those wishing to receive explanations about research content before submitting the application must contact a supervisor in their desired field of research.
Please contact the Secretariat via e-mail if you’re unsure of the supervisor’s contact information (gakusei(at)kyu-dent.ac.jp). Please include the following items 1-5 in the e-mail.
At a later date, a representative in your desired field of research will contact you.

1. Name
2. Name of the university you graduated
3. Phone number
4. E-mail address
5. Desired field of research (name of the teacher if you know)

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